Bacterial meningitis occurs sporadically in lambs. It most commonly affects lambs 2 to 4 weeks old. The entry point of the bacteria is not clearly understood. Inadequate transfer of passive antibodies predisposes lambs to infection. Early clinical signs include depression, hunger, and failure to follow dams. Affected lambs may have abnormal gait. Their head is often held lower in a rigid extension. Response to treatment with antibiotics and corticosteroids is usually poor.